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24 Apr
2019

A*Star inks US$90m deal to create deep tech startups in healthcare, life sciences

<The Business Times>

THE Agency for Science, Technology and Research (A*Star) enterprise arm A*ccelerate on Wednesday signed a US$90 million agreement with Nasdaq-listed pharmaceutical firm Aptorum Group and Hong Kong financial institution Aeneas Capital to co-create local deep tech startups in healthcare and life sciences.

In the latest of a series of venture co-creation agreements, Aptorum and A*ccelerate aim to create up to 20 deep tech ventures in Singapore over the next five years. These startups will tap technologies co-developed by A*Star research institutes and Aptorum, and will get help with being connected to relevant market partners and clients via Aptorum's global network.

One area being explored is surgical imaging solutions in surgical robotics. This would involve applying A*Star's capabilities in medical image analytics and augmented reality, to real-time 2D and 3D magnetic resonance imaging (MRI) surgical imaging solutions.

A*ccelerate chief executive officer Philip Lim said: "This agreement is testament to the vibrancy of Singapore's biotech ecosystem, as well as the private sector's confidence in A*Star's capabilities in deep tech and biomedical research."

Ian Huen, founder and CEO of Aptorum as well as founder of Aeneas Capital, expressed his strong belief that the partnership will yield "strong venture businesses that will be eventually recognised worldwide".

Separately, Aptorum Group and Aeneas Capital will also launch a healthcare and life science strategic investment fund of up to US$200 million, which might be used to invest in the local biotech ecosystem. The two parties will also make acquisitions in identified technologies and businesses globally.

(Source: https://www.businesstimes.com.sg/government-economy/astar-inks-us90m-deal-to-create-deep-tech-startups-in-healthcare-life-sciences)

24 Apr
2019

Aptorum Group Limited Announces Repurchase of USD13,500,000 outstanding Convertible Bonds Due 2019

<The New York Times>

Aptorum Group Limited (NASDAQ: APM) (“Aptorum” or the “Company”), a pharmaceutical company focused on the development and commercialization of therapeutic and diagnostic technologies to tackle unmet medical needs, announced today that the Company, in a privately-negotiated transaction, repurchased all outstanding US$13,500,000 in aggregate principal amount of the 8.00 per cent. convertible bonds due 2019 (“Convertible Bonds”) from Peace Range Limited, a wholly owned subsidiary of Adamas Ping An Opportunities Fund LP, together with certain subscription right to subscribe up to the principal amount of the Bond at a US$12.17 (subject to adjustment) on or before December 17, 2019 (“Subscription Right”).

The total consideration of the repurchase of the Convertible Bonds and the Subscription Right was US$13.6 million in cash, excluding accrued interest. The repurchase of the Convertible Bonds and Subscription Right was executed by Aptorum Investment Holding Limited, a wholly owned subsidiary of Aptorum Group Limited. Pursuant to the repurchase, Aptorum Group would not have any outstanding group liabilities in respect of the Convertible Bonds or Subscription Right.

About Aptorum Group Limited
Aptorum is a pharmaceutical company dedicated to developing and commercializing a broad range of therapeutic and diagnostic technologies to tackle unmet medical needs. Aptorum is pursuing therapeutic and diagnostic projects in neurology, infectious diseases, gastroenterology, oncology and other disease areas; on the other hand, it also houses projects focused on non-therapeutic areas such as surgical robotics as well as the operations of its medical clinic in Hong Kong, Talem Medical, with the initial focus on treatment of chronic diseases resulting from modern sedentary lifestyles and aging population.

For more information about the Company, please visit www.aptorumgroup.com.

Forward-Looking Statements
This press release includes statements concerning Aptorum Group Limited and its future expectations, plans and prospects that constitute “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. For this purpose, any statements contained herein that are not statements of historical fact may be deemed to be forward-looking statements. In some cases, you can identify forward-looking statements by terms such as “may,” “should,” “expects,” “plans,” “anticipates,” “could,” “intends,” “target,” “projects,” “contemplates,” “believes,” “estimates,” “predicts,” “potential,” or “continue,” or the negative of these terms or other similar expressions. Aptorum has based these forward-looking statements largely on its current expectations and projections about future events and trends that it believes may affect its business, financial condition and results of operations.

These forward-looking statements speak only as of the date of this press release and are subject to a number of risks, uncertainties and assumptions including, without limitation, risks related to its announced management and organizational changes, the continued service and availability of key personnel, its ability to expand its product assortments by offering additional products for additional consumer segments, Aptorum Group Limited’s anticipated growth strategies, anticipated trends and challenges in its business, and its expectations regarding, and the stability of, its supply chain, and the risks. These are disclosed in Aptorum Group Limited’s reports filed from time to time with the Securities and Exchange Commission, including its most recent Form 20-F and any subsequent filings, available at www.sec.gov. Readers are urged not to place undue reliance on these forward-looking statements, which speak only as of the date of this press release. Aptorum does not intend to update any forward-looking statement contained in this press release to reflect events or circumstances arising after the date hereof.

This press release does not constitute an offer to sell, or a solicitation of an offer to buy, any securities, and it does not constitute an offering prospectus within the meaning of Section 27A of the Securities Act of 1933 and Section 21E of the Securities Exchange Act of 1934. Investors must rely on their own evaluation of Aptorum Group Limited and its securities, including the merits and risks involved. Nothing contained herein is or shall be relied on as, a promise or representation as to the future performance of Aptorum Group Limited.

(Source: https://markets.on.nytimes.com/research/stocks/news/press_release.asp?docTag=201904240415BIZWIRE_USPRX____BW5389&feedID=600&press_symbol=507158038)

24 Apr
2019

Aptorum Group’s Smart Pharma announces launch of its asset backed Smart Pharma token (SMPT), supported by its computational repurposed drug discovery platform Smart-ACT™

<The New York Times>

VICTORIA, Seychelles--(BUSINESS WIRE)--Apr. 24, 2019-- Aptorum Group Limited (Nasdaq:APM) is excited to announce the launch and issuance of its asset backed Smart Pharma Token (“SMPT”) by its wholly owned subsidiary group, Smart Pharma group and Smart Pharmaceutical Limited Partnership (“SPLP”) targeted in May 2019.

SPLP is extremely pleased to have jointly developed the SMPT token with Aenco, an affiliated blockchain development company focused on applications in the healthcare and financial sector. The SMPT token, an ERC-1404 security compliant token, is a unique token that tokenizes valuable pharmaceutical drugs and their underlying intellectual property and associated allocation of cash flows induced by continual product development and commercialization. It is the intention of the Smart Pharma group to continue to incorporate Aenco’s blockchain technology into its pharmaceutical development and commercialization processes.

Relying on intellectual property derived from the Smart-ACT™ platform, Smart Pharma’s in-house new and repurposed drug discovery program, we believe it will revolutionize drug discovery, in particular, drug repurposing and repositioning. Smart-ACT™ stands for Accelerated Commercialization of Therapeutics and encompasses state-of-the-art technology in systematic screening of existing approved drug molecules against selected therapeutic targets. Specifically, the Smart-ACT™ platform comprises a network of modules and processes that simulate the effectiveness of drug molecules against diseases for outcome prediction and selection. The Smart-ACT™ platform, in combination with in vitro and in vivo validation studies, will initially focus on the screening for drugs targeting orphan diseases or unmet medical needs with a target to discover up to 10 new and promising drug candidates per annum.

The SMPT token is created to help foster a community ecosystem of passionate and like-minded people in revolutionising the drug discovery industry who would like to be an integral part of the process. SMPT token is backed by SPLP’s assets, including intellectual property rights of drug candidates created through the Smart-ACT™ program and any royalty monetization income. The SMPT tokens are backed by the following:

intellectual property rights obtained from drug candidates discovered;
applicable royalties based on net sales of the licensed products made by Smart Pharma group upon successful commercialization of the drugs;
a percentage of sublicensing revenue received by Smart Pharma group from third party in regard to the licensed intellectual property rights; and
a percentage of consideration for assignment of the intellectual property rights to third parties.
SMPT token holder will allow them to benefit from the inherent valuation growth of SPLP’s intellectual property portfolio as well as being entitled to a portion of cash flows both upon any winding-up of SPLP or upon distributions by SPLP (distributions can be made periodically at SPLP’s discretion).

A spokesperson for Smart Pharma commented: “Our Smart-ACT™ platform is a novel tool that will completely transform the drug repurposing and discovery industry which traditionally relied on scattered and serendipitous discoveries, with initial focus on orphan and unmet diseases and backed by its parent company, Aptorum Group Limited. We are excited to invite like-minded community and participants to join and benefit from our exciting initiatives, through the SMPT token.”

SPLP plans to collaborate with a number of third party exchanges to establish a secondary market for the SMPT token in Q2 2019 and further information will be made available on its website and social media platforms. The SMPT token will not be available for offer or sale to participants who are residents of the United States and certain other countries. All SMPT token holders will need to undergo a “whitelisting” procedure through the SMTPH.com website in order to qualify for holding of the token, which will involve compliance with know your customer (KYC) and applicable anti-money laundering (AML) procedures.

Further information on the Smart-ACT™ platform can be found on our website: http://www.smtph.com.

Further information on the Smart Pharma Token, SMPT, can be found on our website: http://www.smtph.com/token.

Further information on Aenco can be found on the website: http://www.aencoin.com.

About Aptorum Group Limited

Aptorum Group Limited (Nasdaq:APM) is a pharmaceutical company dedicated to developing and commercializing a broad range of therapeutic and diagnostic technologies to tackle unmet medical needs. Aptorum Group is pursuing therapeutic and diagnostic projects in neurology, infectious diseases, gastroenterology, oncology and other disease areas as well as non-therapeutic areas such as surgical robotics and the operations of its medical clinic in Hong Kong, Talem Medical, with the initial focus on treatment of chronic diseases resulting from modern sedentary lifestyles and aging population.

For more information about Aptorum Group, please visit www.aptorumgroup.com.

About Smart Pharma

Smart Pharma’s holding company, SMTPH Limited, and its group companies are wholly-owned subsidiaries of Aptorum Group Limited, focuses on deploying its Smart-ACT™ platform to revolutionize pharmaceutical discovery and development.

For more information about Smart Pharma, please visit www.smtph.com.

Disclaimer and Forward-Looking Statements

This press release includes statements concerning Aptorum Group Limited and its future expectations, plans and prospects that constitute “forward-looking statements” within the meaning of the Private Securities Litigation Reform Act of 1995. For this purpose, any statements contained herein that are not statements of historical fact may be deemed to be forward-looking statements. In some cases, you can identify forward-looking statements by terms such as “may,” “should,” “expects,” “plans,” “anticipates,” “could,” “intends,” “target,” “projects,” “contemplates,” “believes,” “estimates,” “predicts,” “potential,” or “continue,” or the negative of these terms or other similar expressions. Aptorum Group has based these forward-looking statements largely on its current expectations and projections about future events and trends that it believes may affect its business, financial condition and results of operations. These forward-looking statements speak only as of the date of this press release and are subject to a number of risks, uncertainties and assumptions including, without limitation, risks related to its announced management and organizational changes, the continued service and availability of key personnel, its ability to expand its product assortments by offering additional products for additional consumer segments, the company’s anticipated growth strategies, anticipated trends and challenges in its business, and its expectations regarding, and the stability of, its supply chain, and the risks more fully described in Aptorum Group’s Form 20-F and other filings that Aptorum Group may make with the SEC in the future. Aptorum Group assumes no obligation to update any forward-looking statements contained in this press release as a result of new information, future events or otherwise.

This communication shall not constitute an offer to sell or the solicitation of an offer to buy any securities, nor shall there be any sale of securities in any jurisdiction in which the offer, solicitation or sale would be unlawful prior to the registration or qualification under the securities laws of any such jurisdiction. No offering of securities shall be made except by means of a prospectus meeting the requirements of Section 10 of the Securities Act of 1933, as amended.

Investors must rely on their own evaluation of Aptorum and its securities, including the merits and risks involved. Nothing contained herein is or shall be relied on as, a promise or representation as to the future performance of Aptorum Group or Smart Pharma group.

(Source: https://markets.on.nytimes.com/research/stocks/news/press_release.asp?docTag=201904240430BIZWIRE_USPRX____BW5097&feedID=600&press_symbol=507158038)

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